XWH - 04 - 1 - 0046 TITLE : Identify the impact of TGF - ß signaling on the stroma in the progression of prostate cancer PRINCIPAL INVESTIGATOR : Neil

نویسنده

  • Neil A. Bhowmick
چکیده

• Placencio, V.R., Sharif-Afshar, A.-R., Simon W. Hayward, and Bhowmick N.A. (2005) Prostatic Epithelial Transformation and Androgen Responsiveness Regulated by Stromal-Epithelial Interactions. (oral presentation) Society For Basic Urologic Research Meeting. Miami, FL. Awards received based on work supported by this grant None Products CDNA construct, cell lines, and animal models developed • Development of a in vivo tissue recombination model that incorporates large T antigen expressing prostatic epithelia with stromal cells defi cient in TGFß responsivity. • Transgenic mouse line termed FßKO/TOPGal that enables the study of canonical Wnt signaling in the context of stromal cells defi cient for TGFß responsivity.

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TITLE : Identify the impact of TGF - ß signaling on the stroma in the progression of prostate cancer

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تاریخ انتشار 2006